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NCI-H661 人大細(xì)胞肺癌細(xì)胞

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NCI-H661 人大細(xì)胞肺癌細(xì)胞

ATCC® Number:  HTB-183™

Designations:  NCI-H661 [H661]

Depositors:   AF Gazdar, JD Minna

Biosafety Level: 1

Shipped:  frozen

Medium & Serum:  See Propagation

Growth Properties: adherent

Organism: Homo sapiens (human)

Morphology: epithelial

NCI-H661 人大細(xì)胞肺癌細(xì)胞

Source: Organ: lung

Disease: carcinoma; large cell lung cancer

Derived from metastatic site: lymph node

Permits/Forms: In addition to the MTA mentioned above, other ATCC and/or regulatory permits may be required for the transfer of this ATCC material. Anyone purchasing ATCC material is ultimay responsible for obtaining the permits. Please click here for information regarding the specific requirements for shipment to your location.


Isolation:  Bethesda Maryland,

Isolation date: 1982

DNA Profile (STR): Amelogenin: X,Y

CSF1PO: 10

D13S317: 11

D16S539: 12

D5S818: 11

D7S820: 8,10

THO1: 8

TPOX: 8

vWA: 17

Cytogenetic Analysis: hyperhexaploid; modal number = 142; range = 130 to 153. Each cell had over 70 marker chromosomes. Among the markers were t(1p10q), del(1)(q11/q12), 6q+, 2q+,der(20)t(12;20)(q11;q13). Some of these had 2 to copies per cell. Most cells also had 5 to 10 microchromosomes (metacentric like). Structurally normal N2,N4 and N9 were absent; two copies of the X and multiple copies of the Y were detected.

Isoenzymes:  AK-1, 1

ES-D, 1

G6PD, B

GLO-I, 1-2

Me-2, 0

PGM1, 1

PGM3, 1

Age:  43 years

Gender:  male


















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